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Sci-Afric Journal of Scientific Issues, Research and Essays (SJSIRS)

Sci-Afric Journal of Scientific Issues, Research and Essays Vol.5(8) Pp. 078-083 August 2017 Copyright 2017 Sci-Afric Publishers.

 

Phytochemical Screening and Antimicrobial Activity of Ximenia americana

Ushie O.A*1, Egwaikhide, P.A2 and Longbab B.D3


1, 2, & 3Department of Chemical Sciences, Federal University, Wukari Nigeria


*Corresponding Author email: afiushie@yahoo.com
   

      

Accepted August 07th, 2017

Abstract

The method of cold maceration was used in the extraction by serial exhaustive extraction method. Phytochemical examinations were carried out for all the extracts using standard procedures to identify the constituents. The phytochemical screening of crude extracts of Ximenia americana revealed that alkaloids, tannins, terpenoids, flavonoids and steroids. The crude extracts were tested for antibacterial and antifungal activities. All the crude extracts of the leaf inhibited or exhibited antibacterial activity against all the bacteria pathogens tested with a diameter that ranged between 8 – 21 mm. All the crude extracts of the leaf inhibited or exhibited antifungal activity against all the fungi pathogens tested with a diameter that ranged between 8 - 14 mm except hexane and ethyl acetate extracts that did not show significant inhibition against A. niger. The minimum inhibitory activity (MIC) of the extracts of Ximenia americana against tested microbes ranges from 400 to 100 mg/ml in almost all the extracts and in few instance 50 mg/ml against the tested bacteria.
 

 

Keywords: Phytochemica, Antimicrobial Activity, Ximenia americana, serial exhaustive extraction, minimum inhibitory activity.


 

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